Spine surgeons: spine industry : Eur.Spine J. 2007, S. R. Garfin UCSD

[Slackwater]

Printed this out at UCSF med.school last year. The article is enlightening. Similar issues come up in Computer Science where grant money from a specific donor can create aspersions of bias, so ...

New product development, take stem cells. I want an orthobiologic solution, instead of fusion. Front page of the paper this morning said FDA ... stops ...., well it's the San Jose Mercury News, so ...

The question is how do new medical products get developed? Government is not going to pay the full Research and Development costs of orthobiologic intervertebral disc solutions, or artificial disc, or artificial hips, ankles, knees, and ... next ...

Everybody raise their hand who wants our current executive branch of government to make decisions about orthobiologics. Let's count, ... (I may need to edit this).


~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

PMID: 18027002
Eur Spine J. 2007 Nov 20. [Epub ahead of print]

Spine surgeons: spine industry.

Garfin SR.
Department of Orthopaedic Surgery, UCSD, 200 West Arbor Drive, San Diego, CA, 92103-8894

"Spine surgeons and the spine industry are intimately related. There has been a significant amount of bad press and some apprent Academic / Medical Society repercussions and or negative aspersions when research is reported which has been supported from industry grants [7, 8, 10, 11, 14, 16]. My bias is that industry funds are not (or need not) be bad, or seen as tainted.

We are currently seeing decrease funding available from US (and possibly other) government research funding organizations. There is decreased money in Academic Medical Centers to support the basic academic requirements such as teaching, let alone money for pilot studies[1]. Clinical revenues are decreasing, monies which some physicians (private practice and/or University based) use in their group to support research."
...
"On the other hand some physicians not invited into the trials early may become mad, insulted, angry, and try to denigrate the studies, perhaps for selfish (jealous), rather than purely scientific reasons."
....

"I thank the editors of the European Spine Journal who heard this talk and respected my thoughts enough to ask me to prepare this, and the Chilean Orthopaedic and Traumatology Society (and Julio Urratia, M.D., its' Spine Program Chair) where this was first presented at their November 2005 annual meeting. I would also like to thank David Shaw, J.D., Vice President, Legal Affairs, General Counsel from Kyphon, Inc., Ed Crowe, former Vice President of Marketing, DePuy Spine, Inc., David Amiel, Ph.D., Professor of Biochemistry at UCSD Department of Orthopaedic Surgery, and Richard Lieber, Ph.D., Professor of Muscle Physiology at UCSD Department of Orthopaedic Surgery, for their insights and furthering my education / understandingin the development of this paper."

References:
1. Brand RA, Buckwalter JA, Talman CL., Happe DG (2003) Industrial support of orthopaedic researhin the academic setting. Clin Orthop 412:45-53

2. Cruess RL, Cruess SR, Johnston SE (2000) Professionalism and medicine's social contract. J Bone Joint Surg 82; 1189-1194

3. Crowninshield R (2003) The orthopaedic prfession and industry; conflict or convergence of interests. Clin Orthop 412:8-13

4. Crowninshield R (2005) The orthopaedic profession and the orthopaedic industry: partners in quality patient care. J Bone Joint Surg Am 85:164

5. DeAngelis CD (2000) Conflict of interest and the public trust. JAMA 284(17): 237-238

6. DelSignore JL (2003) Current guidelines regarding industry-sponsored continuing medical education. Clin Orthop 412:21-27

7. Epps CH (2003) Ethical guidelines for orthopaedists and industry. Clin Orthop 412: 293-301

8. Leopold SS, Warne WJ, Braunlich EF, Shott S (2003) Association between funding source and study outcome in orthopaedicresearch. Clin Orthop 415: 293-301

9. Lim E, Aquino NJ (1999) The orthopaedic surgeon and manufacturing industry relationship: ethical guidelines. Clin Orthop 368:279-286

10. Lubahn JD, Mankin CJ, Mankin JH, Kuhn PJ (2000) Orthopaedics, ethics and industry: appropriateness of gifts, grants and awards. Clin Orthop 371: 256-263

11. Sarmiento A (2003) The relationship between orthopaedics and industry must be reformed. Clin Orthop 412: 38-44

12. Saroff D (2005) Objectivity and worldly wisdom: missing ingredients in orthopaedic training and practice. J Bone Joint Surg Am 85: 166

13. Shah RV, Albert TJ, Bruegel-Sanchez V, Vaccaro AR, Hillbrand AS, Grauer JN (2005) Industry support and correlation to study outcome for papers published in spine. Spine 30(9):1099-1104

14. Wenger NS, Lieberman JR (2000) The orthopaedic surgeon and industry: ethics and industry incentives. Clin Orthop 378: 39-43

15. Wieting MW, Mevis H, Zuckerman JD (2003) The role of industry in internet education. Clin Orthop 412: 28-32

16. Wilson FS (2003) Continuing medical education: ethical collaboration between sponsor and industry. Clin Orthop 412: 33-37

17. Wurth GR, Sherr, JH, Coffman TM (2003) Orthopaedic research and education foundation industry. Clin Orthop 412:54-56

~~~~~~~~~~~~~~~~~~~~~~~


Slackwater
mva: 2-level lumbar surgery candidate